Gastric bypass surgery reveals independency of obesity and diabetes melitus type 2
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چکیده
منابع مشابه
Gastric bypass surgery reveals independency of obesity and diabetes melitus type 2
BACKGROUND Roux-en-Y gastric bypass surgery is widely applied to ameliorate morbid obesity, including diabetes in people with type 2 diabetes. The latter vanish a few days after surgery for many, but not in all patients before any weight reduction has occurred. The explanation for this change in metabolic status is poorly understood, but the observation may suggest that the fate obesity and dia...
متن کاملEffects of Gastric Bypass Surgery in Patients With Type 2 Diabetes and Only Mild Obesity
OBJECTIVE Roux-en-Y gastric bypass (RYGB) ameliorates type 2 diabetes in severely obese patients through mechanisms beyond just weight loss, and it may benefit less obese diabetic patients. We determined the long-term impact of RYGB on patients with diabetes and only class I obesity. RESEARCH DESIGN AND METHODS Sixty-six consecutively selected diabetic patients with BMI 30-35 kg/m(2) underwen...
متن کاملImpact of Gastric Bypass Surgery on Gut Hormones and Glucose Homeostasis in Type 2 Diabetes
Gastric bypass surgery (GBP) for obesity, by constructing an isolated 30-ml proximal gastric pouch connected to a 75-cm limb of proximal jejunum, bypassing >90% of the stomach, the pylorus, and the duodenum, cures type 2 diabetes in >80% of cases. We review alterations in gastrointestinal peptide release after GBP that affect glucose disposal. We focus on ghrelin and the incretins glucosedepend...
متن کاملRefractory hyperglycemia after gastric bypass surgery: a novel subtype of type 2 diabetes?
Patients failing to respond to radically effective therapies can provide clues to identify distinct disease subtypes. For example, the recognition of insulinsensitive and insulin-insensitive patients helped reveal diabetes variants now classified as type 1 and 2. After Roux-en-Y gastric bypass (RYGB), 40–80% of patients with type 2 diabetes (T2DM) experience diabetes remission, and nearly all e...
متن کاملMetabolic surgery: gastric bypass for the treatment of type 2 diabetes mellitus.
Type 2 diabetes mellitus (T2DM) is one of the largest health emergencies of the 21st century given the worldwide increase of obesity during the last decades and its close association. T2DM is an inherited, polygenic and chronic disease caused by the interaction between several genetic variants in genes and the environment. The continuous search for new and more effective tools to achieve approp...
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ژورنال
عنوان ژورنال: BMC Endocrine Disorders
سال: 2016
ISSN: 1472-6823
DOI: 10.1186/s12902-016-0140-8